Development of a Cost-effective Method for Isolating Fucoidan from G. Fucus Algae and Determination of its Biological Activity

The final qualification work is devoted to the study of the biological properties of fucoidan extracted from brown algae and the selection of the most effective method of extraction. The relevance of the selected topic is confirmed by the necessity of developing a cheap and effective technology for obtaining this polysaccharide for use in various regions. The purpose of this work was to improve the method of obtaining dry fucoidan, to determine its functional properties and to study the economic feasibility of using this polysaccharide. In the "Literature review" section, modern domestic and foreign publications are considered regarding the structure of fucoidan, methods of its isolation, biological properties of sulfated polysaccharide, possibilities of its application in the pharmaceutical, cosmetic, food industry, medicine and BAV production. Here is a description of the suitable raw material available for processing in Russia. The economic advantages of already existing methods of fucoidan extraction from brown algae are described. In the section «Materials and methods» there is a description of the methods used and developed during the execution of the work. Objects of research were natural polysaccharides fucoidan. The results of the work are presented in the “Results and Discussion” section. During the work, the conditions for the isolation of fucoidan were selected, its functional properties and antimicrobial activity were determined. The advantages of these conditions and methods used in the isolation of fucoidan are outlined. It has been established that fucoidan has good sorption capacity, is effective as an antimicrobial component and, when modified by thermolysis, has high water and fat-retaining properties. The qualification thesis is completed in 66 pages, including 12 illustrations, 9 tables, the bibliography contains 105 names.