An international team of researchers, including neuroscientists at HSE University, has developed a computational model for simulating semantic dementia, a severe neurodegenerative condition that progressively deprives patients of their ability to comprehend the meaning of words. The neural network model represents processes occurring in the brain regions critical for language function. The results indicate that initially, the patient's brain forgets the meanings of object-related words, followed by action-related words. Additionally, the degradation of white matter tends to produce more severe language impairments than the decay of grey matter. The study findings have been published in
Scientific Reports.