Tag "International Laboratory of Microphysiological Systems"

Our results show that the design of shRNA affects its processing by RNase-III Dicer and can result in the generation of undesirable 5'-isoforms of miRNA/siRNA encoded within the shRNA. This effect is especially significant for miRNA/siRNA longer than 19 nt.

20 марта 2023 г. в рамках конференции «Наукоемкие лабораторные технологии для клинической практики»  на секции, посвященной опухолевым маркерам сотрудница Международной лаборатории микрофизиологических систем Мария Янова выступила с докладом «Маркеры эффективности химиотерапии с использованием гемцитабина у больных раком мочевого пузыря».

Researchers from the Faculty of Biology and Biotechnology at the Higher School of Economics conducted a joint study with colleagues from National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, Center for Digital Biodesign and Personalized Health Care (Sechenov University) and Institute of Bioorganic Chemistry of the Russian Academy of Sciences, dedicated to the study of the link between low expression of the IGFBP6, ELOVL5 genes and lipid metabolism in breast cancer cells. The results of the study will be published in the journal Frontiers in Molecular Biosciences.