Мальцева Диана Васильевна

Education and Degrees

2009

Candidate of Sciences* (PhD)
Lomonosov Moscow State University

2005

Specialist in Chemistry
Lomonosov Moscow State University, Department of Chemistry

* Candidate of Sciences
According to the International Standard Classification of Education (ISCED) 2011, Candidate of Sciences belongs to ISCED level 8 - "doctoral or equivalent", together with PhD, DPhil, D.Lit, D.Sc, LL.D, Doctorate or similar. Candidate of Sciences allows its holders to reach the level of the Associate Professor.

Continuing education / Professional retraining / Internships / Study abroad experience

The additional professional program "Examination and registration of medicines", The Federal State Budgetary Institution “Scientific Centre for Expert Evaluation of Medicinal Products” of the Ministry of Health of the Russian Federation (2014 year)

The additional professional program "Organization and conduct of preclinical studies of drugs - GLP", The Federal State Budgetary Institution “Scientific Centre for Expert Evaluation of Medicinal Products” of the Ministry of Health of the Russian Federation (2014 year)

Professional Interests

Molecular mechanisms of the dissemination and metastasis of cancer Role of extracellular matrix in metastasis Role of cell adhesion molecules in metastasis Organ-on-a-chip microphysiological system human intestine in vitro model Epigenetic mechanisms of gene expression micro RNAs DNA methylation DNA-methyltransferases

Awards and Accomplishments

Winner of the HSE University Best Russian Research Paper Competition – 2022

Courses (2024/2025)

Biochemistry (Bachelor’s programme; Faculty of Biology and Biotechnology; 2 year, 1, 2 module)Rus
Past Courses

Timetable for today

Full timetable

Conferences

2022
I международная конференция «Генетические технологии в трансляционной биомедицине» (Томск). Presentation: Нокдаун а5 цепи ламининов приводит к частичной дедифференцировке клеток колоректального рака и увеличивает их чувствительность к химиотерапии

2021
the Vth Sechenov International Biomedical Summit 2021 (SIBS-2021) (Москва). Presentation: Knockdown of CD44 prevents metastasis in HT-29 xenograft colorectal cancer model

Employment history

Head of Laboratory, International Laboratory of Microphysiological Systems, Faculty of Biology and Biotechnology, National Research University Higher School of Economics (2020 - present time)

Leading Researcher, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences (2019 - 2020)

Principal Investigator at Hertsen Moscow Oncology Research Center, Branch of Federal State Budgetary Institution National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Moscow, Russia (2018 - 2019)

Deputy director for Science at Scientific Research Center Bioclinicum, Moscow, Russia (2014 - 2018)

Group leader at Scientific Research Center Bioclinicum, Moscow, Russia (2012 - 2014)

Postdoctoral research at Department of Molecular Physiology, Russian Research Institute of Physical Education and Sport, Moscow, Russia (2009 - 2012)

Researcher, The A.N. Belozersky Institute Of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia (2008 - 2009)

3

Sep

2024

Biologists at HSE University Warn of Potential Errors in MicroRNA Overexpression Method

Researchers at HSE University and the RAS Institute of Bioorganic Chemistry have discovered that a common method of studying genes, which relies on the overexpression of microRNAs, can produce inaccurate results. This method is widely used in the study of various pathologies, in particular cancers. Errors in experiments can lead to incorrect conclusions, affecting the diagnosis and treatment of the disease. The study findings have been published in BBA.

15

Jul

2022

Seminar: gene overexpressionSeminar

On June 24, 2022, the International Laboratory of Microphysiological Systems hosted a joint seminar with the Laboratory for Research on the Molecular Mechanisms of Longevity, dedicated to the issue of miRNA overexpression in human cells, a process that leads to an excess amount of transcript produced by the genome.

11

Feb

2022

Biologists Figure Out How Stem Cells Turn Into Other Types of Cells at Molecular Level

An international team of researchers including biologists from HSE University has developed a method that helps obtain information on changes in protein expression and properties during cells’ transition from one state to another. One of the most interesting transitions is the transformation of cells from undifferentiated stem cells to differentiated cells of various organs and tissues. The paper was published in Nature Communications.

14

Nov

2021

Members of the International Laboratory of Microphysiological Systems Took Part in SIBS-2021

The 5th Sechenov International Biomedical Summit (SIBS - 2021) was held on November 9-10, 2021 at FSAU VO Sechenov Russian Ministry of Health (Sechenov University). It is one of the most authoritative forums in the country in the field of advanced bioengineering, regenerative and personalized medicine.

14

Sep

2021

Members of the International Laboratory of Microphysiological Systems and the Laboratory of Molecular Physiology participated in RECOMB 2021

25th International Conference on Research in Computational Molecular Biology (RECOMB 2021) was held online on August 29th - September 2nd. Staff of the Faculty of Biology and Biotechnology - Stepan Nersisyan, Alexey Galatenko, Diana Maltseva and Alexander Tonevitsky participated in a poster session with the report 'miRGTF-net: Integrative miRNA-gene-TF network analysis reveals key drivers of breast cancer recurrence'

15

Dec

2020

International Laboratory of Microphysiological Systems at the conference 2020 - International Conference on Research inLife-Sciences & Healthcare (ICRLSH)

On December 11-12, 2020, employees of the International Laboratory of Microphysiological Systems made a presentation at the conference 2020 – International Conference on Research in Life-Sciences & Healthcare (ICRLSH), London, UK

Diana Maltseva