Князев Евгений Николаевич

Education and Degrees

2016

Candidate of Sciences* (PhD) in Oncology
Thesis Title: MicroRNA markers for minimally invasive diagnosis of prostate cancer

2013

Degree in Medicine
Lomonosov Moscow State University, Faculty of Medicine

* Candidate of Sciences
According to the International Standard Classification of Education (ISCED) 2011, Candidate of Sciences belongs to ISCED level 8 - "doctoral or equivalent", together with PhD, DPhil, D.Lit, D.Sc, LL.D, Doctorate or similar. Candidate of Sciences allows its holders to reach the level of the Associate Professor.

Continuing education / Professional retraining / Internships / Study abroad experience

2015-2016, Moscow State University of Medicine and Dentistry named after A. I. Evdokimov, Faculty of Additional Professional Education, an internship in Clinical Pathology and Laboratory Diagnostics

2023, HSE University, Academic Writing Center, course "Preparing a Manuscript for Publication"

2024, HSE University, advanced training on the program "Conflict Management in Educational Environment", specialization "Pedagogical Education".

2024, HSE University, advanced training on the program "Basic Concepts of Artificial Intelligence and its Application for Problem Solving within the Specialty (Advanced Level)".

Professional Interests

Biochemistry oncology human intestine in vitro model bioinformatics personalized medicine cancer biology cell biology 3D cell models microfluidics microphysiological systems molecular biology placental barrier

Awards and Accomplishments

Best Teacher — 2024
Winner of the HSE University Best Russian Research Paper Competition – 2023
Young Faculty Support Programme (Group of Young Academic Professionals)
Category "New Lecturers" (2024)

Courses (2023/2024)

3rd generation Sequencing on Oxford Nanopore (Mago-Lego; 3, 4 module)Rus
Biotechnologies: genetic engineering (Mago-Lego; 3, 4 module)Rus
Fundamentals of statistics. Part 2 (Mago-Lego; 3, 4 module)Rus
Introduction to NGS (Mago-Lego; 3, 4 module)Rus
Project Seminar (Bachelor’s programme; Faculty of Biology and Biotechnology; 3 year, 3 module)Rus
Past Courses

Timetable for today

Full timetable

Conferences

2024
Седьмой онлайн-семинар по математическому моделированию в области иммунологии (Москва). Presentation: Моделирование динамики SARS-CoV-2 в клеточных линиях
Второй Саммит разработчиков лекарственных препаратов «Сириус.Биотех» (Федеральная территория «Сириус»). Presentation: Использование платформы «Человек-на-чипе» при разработке лекарственных препаратов

2019
International Federation of Placenta Associations 2019 (IFPA2019); 8th Latin American Symposium on Maternal-Fetal Interaction and Placenta (VIII SLIMP), Buenos Aires, Argentina (Buenos Aires). Presentation: Placenta-on-a-chip model for assessing the transport and toxicity of xenobiotics in vitro
International Federation of Placenta Associations 2019 (IFPA2019); 8th Latin American Symposium on Maternal-Fetal Interaction and Placenta (VIII SLIMP), Buenos Aires, Argentina (Buenos Aires). Presentation: Application of impedance spectroscopy for analysis of BeWo clone b30 human choriocarcinoma cell line
CTR Annual Conference 2019 (Cambridge). Presentation: Placenta-on-a-chip model for the assessment of drug transport and toxicity
22st European Congress on Alternatives to Animal Testing, 19th Annual Congress of EUSAAT, Linz, Austria (Linz). Presentation: Placenta-on-a-chip model for assessing the transport and toxicity of xenobiotics in vitro
Второй международный форум онкологии и радиологии (Москва). Presentation: Модель плаценты-на-чипе in vitro для оценки транспорта и токсичности химиотерапевтических препаратов
V Всероссийская Конференция по молекулярной онкологии (Москва). Presentation: Модель плаценты-на-чипе in vitro для оценки транспорта и токсичности химиотерапевтических препаратов

Grants

2024-2026 "Microfluidic placenta-on-a-chip model for the study of preeclampsia" (Russian Science Foundation Grant 24-14-00382) - Participant
2023-2026 "The role of miRNA molecules in antitumor and antiviral immunity" (Basic Research Program at HSE University, Statement of Work No. 35) - Principal Investigator
2020-2022 "Coronavirus entry into cells and intracellular transport in the microfluidic model of the intestinal barrier" (RFBR Grant 20-04-60399 ) - Participant
2019-2021 "The role of miRNAs in the placenta-on-a-chip model in simulated hypoxia" (Russian Science Foundation Grant 19-74-00145) - Project Manager
2019-2021 "Transcytosis of exogenous miRNAs in a microfluidic model of the human intestinal barrier" (RFBR Grant 20-34-70092) - Project Manager
2019-2020 "Study of bacterial adhesion in the microfluidic model of the human intestinal barrier" (contract 05.617.21.0056, Ministry of Science and Higher Education of the Russian Federation) - Participant
2017-2019 “Microphysiological model of human placental barrier: Placenta-on-a-chip” (contract 14.588.21.0007, Ministry of Science and Higher Education of the Russian Federation) - Participant
2014-2016 “Development of the analytical assay based on microRNA level in blood plasma for minimally invasive diagnostics of prostate cancer” (contract 14.579.21.0054, Ministry of Education and Science of the Russian Federation) - Participant

Employment history

Dec 2019 — Present: Faculty of Biology and Biotechnology, Head of Laboratory of Molecular Physiology, Associate Professor

May 2019 — Present: Laboratory of Microfluidic Technologies for Biomedicine, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Senior Research Fellow

Feb 2013 — Sep 2023: Translation Technology Center (formerly BioClinicum Laboratory), CEO

Nov 2022 — Jun 2023: Faculty of Biomedical Engineering, Bauman Moscow State Technical University, Associate Professor

Aug 2021 — Feb 2022: Filatov City Clinical Hospital No. 15, Physician of Clinical Laboratory Diagnostics

Feb 2019 — Aug 2019: National Medical Research Center for Therapy and Preventive Medicine, Senior Research Fellow

Sep 2013 — Jun 2015: Laboratory of Cell Physiology, Institute of Biomedical Problems, Research Fellow

Feb 2012 — Jan 2013: Science and Technology Center "Cell Technologies", Research Assistant

1

Oct

2024

HSE University Faculty Members’ Textbook Recognized for Enhancing University Reputation

The textbook titled “Professional Training Internship: Year 1 – A Practical Guide for Students and Educators” by Knyazev E.N. and Chebotareva O.E. has been honored in HSE University's academic achievement awards for its contribution to the institution’s reputation (Level 2).

1

Sep

2024

Laboratory Head E. Knyazev Leads Interactive Discussion as Part of the Open Meetings of the Young Scientists Club

Ahead of the new academic year, Evgeny Knyazev, Head of the Molecular Physiology Laboratory at the Faculty of Biology and Biotechnology, led an interactive discussion on "The Role of Scientific Conferences in a Scientist's Career."

23

Aug

2024

Laboratory Head Evgeny Knyazev Named Among the Best Teachers of Faculty of Biology and Biotechnology

The winners are determined by student voting

16

May

2024

The research from the laboratory was presented at the second Drug Developers Summit "Sirius.Biotech"

As part of the special session "Study of Safety and Biomarkers of New Drugs," a report was given on "The Use of the 'Human-on-a-Chip' Platform in Drug Development"

15

Mar

2024

Grant Application by Faculty of Biology and Biotechnology Supported by the Russian Science Foundation

The project to develop a microfluidic placenta-on-a-chip model for studying various aspects of normal and pathological placental physiology, including one of the severe pregnancy complications—preeclampsia—has won in the competition "Conducting Fundamental and Exploratory Scientific Research by Individual Scientific Groups"

31

Jan

2024

New Study Involving Laboratory Team Published in Placenta Journal in January 2024

The article "MicroRNA miR-27a as a possible regulator of anti-inflammatory macrophage phenotype in preeclamptic placenta" identified a potential therapeutic target for treating preeclampsia.

29

Nov

2023

Evgeny Knyazev, Head of the Laboratory of Molecular Physiology, Took Part in the School of Scientific Leaders in Sochi

From November 26 to December 1, the Scientific Leaders' Offsite School and the III Congress of Young Scientists took place in Sochi and the Sirius Park of Science and Art. Evgeny Knyazev, a member of the Faculty of Biology and Biotechnology at HSE University, participated in these events.

Evgeny Knyazev

Education and Degrees

Continuing education / Professional retraining / Internships / Study abroad experience

Professional Interests

Awards and Accomplishments

Courses (2023/2024)

Courses (2022/2023)

Courses (2021/2022)

Courses (2020/2021)

Timetable for today

Conferences

Grants

Employment history

HSE University Faculty Members’ Textbook Recognized for Enhancing University Reputation

Laboratory Head E. Knyazev Leads Interactive Discussion as Part of the Open Meetings of the Young Scientists Club

Laboratory Head Evgeny Knyazev Named Among the Best Teachers of Faculty of Biology and Biotechnology

The research from the laboratory was presented at the second Drug Developers Summit "Sirius.Biotech"

Grant Application by Faculty of Biology and Biotechnology Supported by the Russian Science Foundation

New Study Involving Laboratory Team Published in Placenta Journal in January 2024

Evgeny Knyazev, Head of the Laboratory of Molecular Physiology, Took Part in the School of Scientific Leaders in Sochi